Btg2 proliferation
WebFeb 10, 2024 · BTG2 was identified a target of miR-27a-3p, and silencing BTG2 weakened miR-27a-3p’s effect. Knocking down ADAMTS9-AS2 abolished sh-YTHDF2’s inhibitory effect on cell proliferation and invasion. Finally, overexpressing ADAMTS9-AS2 restrained xenograft growth. M6A reader YTHDF2-mediated degradation of ADAMTS9-AS2 … WebThe closest homolog of BTG1 is BTG2, which also controls the proliferation and differentiation of adult neural stem cells; the role of BTG2, however, appears to differ from that of BTG1 being probably more relevant in controlling the terminal differentiation of neural stem and progenitor cells in the adult neurogenic niches.
Btg2 proliferation
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WebMigration and invasion enhancer 1 (MIEN1/C35/C17orf37), as an oncogenic gene, is located on chromosome 17q12 and 505 nucleotides from the 3′ end of the ERBB2 oncogene [1,2].Several studies have shown that MIEN1 overexpression results in either disease progression or metastatic propensity in many tumor types, including colon, prostate, … WebJun 15, 2024 · Results: MEG3 was lowly expressed in HCC tissues and cells. Overexpression of MEG3 inhibits the proliferation, migration and invasion of HCC cells. MiR-544b can be sponged by MEG3, and overexpression of miR-544b reverses the anti-cancer effect of MEG3. We further confirmed that BTG2 gene is the target gene of miR …
WebWe revealed that the mechanism of PRMT5-induced proliferation was partially mediated by BTG downregulation, leading to cell cycle arrest during the G1 phase in HCC cells. Ectopic BTG2 overexpression decreased HCC growth, caused cell cycle arrest at the G1 phase, and downregulated Cyclin D1 and Cyclin E1 protein expression. WebHowever, BTG2 may be cancer type-dependent, as overexpression of BTG2 has been demonstrated to suppress the proliferation of pancreatic and lung cancer cells, but promote the proliferation of bladder cancer cells. Since the association between BTG2 and luminal A-subtype breast cancer remains unclear, it is important to understand the biological ...
WebThe B cell translocation gene 1 (BTG1) and BTG2 play a key role in a wide range of cellular activities including proliferation, apoptosis, and cell growth via modulating a variety of central biological steps such as transcription, post-transcriptional, and translation. BTG1 and BTG2 have been identi … WebOct 13, 2024 · B-cell translocation gene 2 (BTG2) is a crucial regulator in GLP-1-induced insulin gene expression and insulin secretion via upregulation of pancreatic duodenal homeobox-1 (PDX-1) in pancreatic beta-cells. These findings demonstrate the gonadotropin stimulation of Btg2 in the ovary and, the physical interaction of Btg2 with Ant2 in …
WebApr 7, 2024 · BTG2 is expressed at low levels in multiple cancers and might therefore act as a tumor suppressor. 25 , 26 , 27 BTG2 plays an important role in cell proliferation, migration, invasion and drug resistance. 28 , 29 Little research has been performed on the biological behavior of BTG2 in response to IR stress.
WebDownload scientific diagram Btg2 Downregulation Leads to Increased Microglia Proliferation (A) Normalized read count of genes involved in microglia proliferation (Hammond et al., 2024). the way filme onde assistirWebThe growth and development of oocyte affect the functional activities of the surrounding somatic cells. These cells are regulated by various types of hormones, proteins, metabolites, and regulatory molecules through gap communication, ultimately leading to the development and maturation of oocytes. The close association between somatic cells and oocytes, … the way finder restaurant estes park coloradoWebMar 6, 2012 · The objective of the study was to investigate the impact of the B cell translocation gene 2 (BTG2) on lung cancer cell growth, proliferation, metastasis, and other biological characteristics and to provide experimental evidence for the biological treatment of human lung cancer. A pcDNA3.1-BTG2 eukaryotic expression vector was … the way first communionWebBTG2基因含有p53野生型基因的反应元件[11]，p73和p53可诱导与人类具有同源性的BTG2基因[12]。利用高密度芯片技术对基因的表达趋势进行研究，发现BTG2基因对细胞的分化、增殖和凋亡起调节作用[13]。 the way fm listen onlineWebThe BTG2 expression is downregulated in many human cancers. It is an instantaneous early response gene and plays important roles in cell differentiation, proliferation, DNA … the way fm charleston scWebFeb 25, 2016 · BTG2 interacts with CAF1 deadenylase through its APRO domain, a defining feature of BTG/Tob factors. ... Importantly, we also show that the interaction of BTG2 with the first RRM domain of PABPC1 is required for BTG2 to control cell proliferation. Publication types Research Support, Non-U.S. Gov't MeSH terms Blotting, Western ... the way fm christian radio dallasProtein BTG2 also known as BTG family member 2 or NGF-inducible anti-proliferative protein PC3 or NGF-inducible protein TIS21, is a protein that in humans is encoded by the BTG2 gene (B-cell translocation gene 2) and in other mammals by the homologous Btg2 gene. This protein controls cell cycle … See more A number of studies in vivo have shown that BTG2 expression is associated with the neurogenic asymmetric division in neural progenitor cells. Tis21-GFP has been used as a neurogenic marker because it is not expressed until … See more BTG2 has been shown to inhibit medulloblastoma, the very aggressive tumor of cerebellum, by inhibiting the proliferation and triggering the differentiation of the … See more • Puisieux A, Magaud JP (April 1999). "[Mechanisms of BTG2 activity, a transcriptional target of p53: evidences and hypothesis]". Bulletin du Cancer. 86 (4): 358–64. See more BTG2 has been shown to interact with PRMT1, HOXB9, CNOT8 and HDAC1 HDAC4 and HDAC9. It has also been studied with See more • Human BTG2 genome location and BTG2 gene details page in the UCSC Genome Browser. • Overview of all the structural information … See more the way fm website