Chrebp chip seq
WebJan 21, 2014 · (A) ChREBP RNA levels during a HCMV infection time course. Total RNA was isolated at 0, 24, 48, and 72 hpi. Total ChREBP RNA levels were measured by qRT-PCR and normalized to actin RNA … WebChREBP Antibody recognizes endogenous levels of total ChREBP protein. Based on amino acid sequence comparisons, the antibody is predicted to detect all known isoforms of ChREBP. Species Reactivity: Human, Mouse, Rat Source / Purification
Chrebp chip seq
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WebTo identify novel ChREBP-regulated hepatokines that contribute to its systemic metabolic effects, we integrated ChREBP ChIP-seq analysis in mouse liver with human genetic … WebNov 16, 2024 · Thyroid hormone action in human hepatocytes and the Cistromes of TRB1 and ChREBP in liver of mice. Human iPSC were differentiated to hepatocytes and …
WebChIP-seq analysis revealed that ChREBP binds to 1153 sites across the genome, 45% of which are located in potential gene regulatory regions including proximal/distal promoters, 5 9 UTRs, and... WebChREBP Is a Central Mediator of Glucose-Induced Transcriptional Reprogramming in b Cells (A–D) INS-1E cells were preincubated with 5 mM glucose for 24 hr and subsequently transduced with equal titers of adenovirus expressing constitutive active ChREBP (CA-ChREBP) or GFP as control.
WebClassification and pathway analysis of genes related to ChREBP binding. A, Frequency of genes identified by anti-ChREBP ChIP-seq that are involved in biological processes. We generated the list of biological processes from WebGestalt using GO slim classification. WebJul 29, 2024 · HGFAC is a ChREBP genomic target that associates with metabolic traits in humans To identify ChREBP transcriptional targets that participate in the regulation of …
WebNov 22, 2024 · To identify novel ChREBP-regulated hepatokines that contribute to its systemic metabolic effects, we integrated ChREBP ChIP-seq analysis in mouse liver with human genetic and genomic data for...
WebThe potential ChoRE for ChREBP binding is highlighted in a red box. C, potential ChoREs in Tug1 promoters of mouse, human, and rat are consensus binding sites for ChREBP. D, ChREBP ChIP-Seq in mouse … round closing strainerWeb20 hours ago · Using ChIP-seq, hepatocyte growth factor activator (HGFAC) was shown to behave as a typical ChREBP target gene, and its expression is statistically significantly increased in mice fed a high ... round clock swivel coverWebMar 1, 2024 · 1. Introduction. Chromatin immunoprecipitation followed by sequencing (ChIP-seq) analysis is a key technology in epigenomic research. This method uses an antibody for a specific DNA-binding protein or a histone modification to identify enriched loci within a genome [1], [2].Histone modifications are used in the ChIP-seq analysis field to … round clothes racks and standsWebMay 13, 2024 · LXR and ChREBP interaction was determined by Co-immunoprecipitation (CoIP) and their transactivity was assessed by real-time quantitative polymerase chain … strategy consulting internWebNov 26, 2024 · Reproducing the ChIP-seq analysis The following is a guide on how to run the scripts used to do the ChIP-seq analysis in Open the LID: LXRα regulates ChREBPα transactivity in a target gene-specific manner through an agonist-modulated LBD- LID interaction. Prerequisites Data The mm9 reference genome, downloaded from here and … round clothing rack for saleWebAug 4, 2024 · To identify novel ChREBP-regulated hepatokines that contribute to its systemic metabolic effects, we integrated ChREBP ChIP-seq analysis in mouse liver with human genetic and genomic data for lipid traits and identified Hepatocyte Growth Factor Activator (HGFAC) as a promising ChREBP-regulated candidate in mice and humans. round clothes railWebAug 30, 2016 · ChREBP RORγ ChIP-seq RNA-seq Introduction Pancreatic β cells play a key role in the regulation of glucose uptake and metabolism. They respond to a rise in blood glucose by increasing the secretion of insulin, which in turn increases the storage and utilization of glucose in peripheral tissues. strategy consulting graduate jobs